DETAILED NOTES ON GENETIC METHYLATION TESTING

cure with sodium bisulfite deaminates unmethylated cytosine to uracil, whereas 5mC is not afflicted. Subsequent PCR amplification will substitute the uracils by thymines. Reads from NGS libraries produced in parallel with and without bisulfite remedy are check here mapped on to reference genomes as well as the contrasting C/T positions among the li